Lisa Kereszi was born in 1973 in Pennsylvania and grew up in Suburban Philadelphia to a father who ran the family auto junkyard and to a mother who owned an antique shop. In 1995 she graduated from Bard College with a Bachelor of Arts.
After college she moved to New York City and worked as an assistant to Nan Goldin. In 2000 she received a Master of Fine Arts degree from the Yale University School of Art in New Haven, Connecticut. She has been on the faculty there as a Lecturer since 2004, and also as Acting Director of Undergraduate Studies in Photography. She was appointed Critic and also Director of Undergraduate Studies in Art in 2013.