Lorena was born in Argentina in 1974.

She studied Anthropology and Architecture and in since 2004 she has been committed to the visual arts. Guillén Vaschetti's work has been widely exhibited and featured in numerous publications. Her first monograph, "historia, memoria y silencios" (Schilt, 2011) was awarded as best book of the year by PDN, United States and Photo España 2012. Recently Vaschetti has moved towards installation-based art. She currently lives and works in Buenos Aires.