Natela Grigalashvili was born in Khashuri, Georgia. Her childhood dream was becoming a cinematographer but photography turned out to be a media which brought more comfort to the artist. Artist was introduced to photography in various studios and established as a photographer after working independently for years.
Grigalashvili was awarded the Alexander Roinishvili Prize for her contribution to Georgian photography in 2007.In the 1990s photographer used to shoot with black-and-white film. For last 10 years, Grigalashvili has been taking color photographs with a digital camera. Artist mainly makes photo series and realizes long-term art projects.While working on a photo series Grigalashvili focuses on the story which is told by the image.

She teaches photography at Tbilisi State University.Artist permanently works on photo projects and travels in different regions of Georgia. Grigalashvili founded photography schools in Javakheti(2014) and in the Pankisi Gorge(2015) and in Adjara(2017).